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TB-5005 / 10 mg
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Recovery · RV-0026
Melanotan-1 (Afamelanotide)
For in-vitro research only.View certificate of analysis
Melanocortin receptor agonist studied in pigmentation-pathway models. For in-vitro research only.
$69.00/ vial
$6.90/mgIn stock
1
For in-vitro research only. Not for human or veterinary use.
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Overview
Melanocortin receptor agonist studied in pigmentation-pathway models. For in-vitro research only.
Store the sealed vial at −20 °C, protected from light and moisture. Once reconstituted, store at 2–8 °C and avoid freeze–thaw cycles.
Bacteriostatic water is added slowly down the inside wall of the vial, then swirled until the cake dissolves. Concentration follows from the diluent volume.
Research summary
- Substituting norleucine at position 4 and D-phenylalanine at position 7 produced a peptide resistant to degradation by serum enzymes with prolonged activity, and 26 times as potent as the parent hormone in a melanoma adenylate cyclase assay. [1]
- Forced degradation under acidic, basic, neutral and oxidative stress, ultraviolet light and elevated temperature produced fourteen separable degradation products, with truncation, methylation, deacetylation and oxidation identified as the pathways. [2]
- A derivative of this analogue prepared for a lead chelator showed sub-nanomolar binding affinity for melanocortin receptor 1 with high selectivity against the closely related melanocortin receptor 4. [3]
- In human articular chondrocyte cultures the analogue partly reduced doxorubicin driven senescence markers, significantly reduced reactive oxygen and nitrogen species, and lowered interleukin 6 secretion without changing matrix metalloproteinase secretion. [4]
Specifications
- Compound
- Melanotan-1 (Afamelanotide)
- Purity
- 99.40% (HPLC)
- Identity
- Confirmed by MS
- Appearance
- White lyophilate
- Presentation
- 10 mg
- Catalog / lot
- RV-0026 / RV-24-0026-1
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or supplement.
Certificate of analysis
Certificate available
- Melanotan-1 (Afamelanotide)
- 99.40%
- Confirmed
- White lyophilate
- < 0.5 EU/mg
- Sample Analytical
- #SAMPLE-0026-1
- 2026-08-14
- J. Alvarez, QA
Review the laboratory, lot identifier, and reported results in this document. Keep the lot identifier with your research records.
All lots of Melanotan-1 (Afamelanotide)Questions
Before you order
Find the lot number on your vial label. Search for it in the certificate archive, or open the linked lot record from your account order.
Compare the listed quantity, price and price per milligram for each available size. Choose the specification required for your laboratory work.
Vials are packed to limit movement and protect the contents during transit. Packaging varies with the items and quantity ordered.
Have any lot assayed by a laboratory of your choice. If the result comes in below our certificate, the order is refunded or replaced.
In-vitro laboratory research only. It is not for human or veterinary use and it is not a drug, food, cosmetic, or supplement.
