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TB-5005 / 10 mg
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Recovery · RV-0019
Melanotan II
For in-vitro research only.View certificate of analysis
Melanocortin receptor agonist studied in pigmentation-pathway models. For in-vitro research only.
$69.00/ vial
$6.90/mgIn stock
1
For in-vitro research only. Not for human or veterinary use.
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- Lot certificate available to review
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- Protective bubble mailer
Overview
Melanocortin receptor agonist studied in pigmentation-pathway models. For in-vitro research only.
Store the sealed vial at −20 °C, protected from light and moisture. Once reconstituted, store at 2–8 °C and avoid freeze–thaw cycles.
Bacteriostatic water is added slowly down the inside wall of the vial, then swirled until the cake dissolves. Concentration follows from the diluent volume.
Research summary
- Varying the lactam ring size across a synthesised series showed a sharp optimum: the 23-membered ring analogues were 100 times as potent as the parent hormone in the lizard skin assay, and both larger and smaller rings were markedly less potent. [1]
- Side-chain topology carries the binding: replacing phenylalanine or tryptophan with alanine gave compounds inactive at micromolar concentrations, replacing arginine gave a hundredfold loss, and replacing histidine changed almost nothing. [2]
- The acetyl-norleucine segment that sits outside the lactam ring has virtually no effect on binding or activation at human melanocortin receptor 4 while being essential for full potency at receptor 5, which is how selective analogues were obtained. [3]
- Replacing the lactam cyclisation with xylene-derived thioether linkers gave affinities spanning low nanomolar to sub-micromolar and produced one compound with marked functional selectivity for human melanocortin receptor 1, unlike the unselective parent. [4]
Specifications
- Compound
- Melanotan II
- Purity
- 99.20% (HPLC)
- Identity
- Confirmed by MS
- Appearance
- White lyophilate
- Presentation
- 10 mg
- Catalog / lot
- RV-0019 / RV-24-0019-1
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or supplement.
Certificate of analysis
Certificate available
- Melanotan II
- 99.20%
- Confirmed
- White lyophilate
- < 0.5 EU/mg
- Sample Analytical
- #SAMPLE-0019-1
- 2026-08-14
- J. Alvarez, QA
Review the laboratory, lot identifier, and reported results in this document. Keep the lot identifier with your research records.
All lots of Melanotan IIQuestions
Before you order
Find the lot number on your vial label. Search for it in the certificate archive, or open the linked lot record from your account order.
Compare the listed quantity, price and price per milligram for each available size. Choose the specification required for your laboratory work.
Vials are packed to limit movement and protect the contents during transit. Packaging varies with the items and quantity ordered.
Have any lot assayed by a laboratory of your choice. If the result comes in below our certificate, the order is refunded or replaced.
In-vitro laboratory research only. It is not for human or veterinary use and it is not a drug, food, cosmetic, or supplement.
