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Metabolic · RV-0021
PT-141
For in-vitro research only.View certificate of analysis
Melanocortin receptor agonist studied in central nervous system signaling models. For in-vitro research only.
$89.00/ vial
$8.90/mgIn stock
1
For in-vitro research only. Not for human or veterinary use.
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Overview
Melanocortin receptor agonist studied in central nervous system signaling models. For in-vitro research only.
Store the sealed vial at −20 °C, protected from light and moisture. Once reconstituted, store at 2–8 °C and avoid freeze–thaw cycles.
Bacteriostatic water is added slowly down the inside wall of the vial, then swirled until the cake dissolves. Concentration follows from the diluent volume.
Research summary
- One of four high resolution structures of full-length melanocortin-4 receptor in complex with heterotrimeric Gs protein was obtained with this peptide as the stimulating ligand, alongside alpha-MSH, afamelanotide and a small molecule. [1]
- Forced degradation under acidic, basic, neutral hydrolytic, oxidative, thermal and photolytic stress produced eight degradation products, with deacetylation, peptide bond hydrolysis, oxidation and epimerization as the major pathways. [2]
- In human glioblastoma cell lines the peptide reduced survivin expression and induced cell death, and an antagonist of melanocortin receptors 3 and 4 cancelled both effects. [3]
- High resolution Orbitrap mass spectrometry established elemental composition and structural features for seized samples labeled as this peptide and as melanotan II, without reference standards for either. [4]
Specifications
- Compound
- PT-141
- Purity
- 99.40% (HPLC)
- Identity
- Confirmed by MS
- Appearance
- White lyophilate
- Presentation
- 10 mg
- Catalog / lot
- RV-0021 / RV-24-0021-1
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or supplement.
Certificate of analysis
Certificate available
- PT-141
- 99.40%
- Confirmed
- White lyophilate
- < 0.5 EU/mg
- Sample Analytical
- #SAMPLE-0021-1
- 2026-08-14
- J. Alvarez, QA
Review the laboratory, lot identifier, and reported results in this document. Keep the lot identifier with your research records.
All lots of PT-141Questions
Before you order
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Compare the listed quantity, price and price per milligram for each available size. Choose the specification required for your laboratory work.
Vials are packed to limit movement and protect the contents during transit. Packaging varies with the items and quantity ordered.
Have any lot assayed by a laboratory of your choice. If the result comes in below our certificate, the order is refunded or replaced.
In-vitro laboratory research only. It is not for human or veterinary use and it is not a drug, food, cosmetic, or supplement.
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